Darrell J Irvine Selected Research

Interleukins

1/2018	Nanoparticle anchoring targets immune agonists to tumors enabling anti-cancer immunity without systemic toxicity.
12/2013	In vivo targeting of adoptively transferred T-cells with antibody- and cytokine-conjugated liposomes.

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Darrell J Irvine Research Topics

Disease

62	Neoplasms (Cancer) 08/2022 - 04/2008
12	Melanoma (Melanoma, Malignant) 01/2022 - 12/2009
11	Infections 01/2020 - 09/2008
6	Bites and Stings (Sting) 08/2022 - 06/2015
4	Human Influenza (Influenza) 11/2022 - 03/2011
4	Inflammation (Inflammations) 06/2020 - 10/2016
3	Neoplasm Metastasis (Metastasis) 01/2022 - 03/2019
3	Malaria 08/2014 - 01/2012
2	Breast Neoplasms (Breast Cancer) 01/2022 - 03/2021
2	Virus Diseases (Viral Diseases) 01/2022 - 01/2014
2	COVID-19 03/2021 - 01/2021
2	Skin Neoplasms (Skin Cancer) 01/2021 - 01/2020
2	Communicable Diseases (Infectious Diseases) 01/2021 - 09/2008
2	Disease Progression 01/2020 - 01/2019
2	Lymphoma (Lymphomas) 11/2018 - 06/2015
2	Wiskott-Aldrich Syndrome 10/2016 - 03/2015
1	Carcinoma (Carcinomatosis) 08/2022
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2022
1	Triple Negative Breast Neoplasms 01/2022
1	Microsatellite Instability 10/2021
1	Anthrax 02/2021
1	Colonic Neoplasms (Colon Cancer) 02/2021
1	Hematologic Neoplasms (Hematological Malignancy) 12/2019
1	Venezuelan Equine Encephalomyelitis 01/2019

Drug/Important Bio-Agent (IBA)

21	AntigensIBA 11/2022 - 09/2008
17	VaccinesIBA 03/2021 - 09/2008
15	CytokinesIBA 01/2022 - 12/2009
14	Proteins (Proteins, Gene)FDA Link 08/2022 - 01/2006
9	Pharmaceutical PreparationsIBA 01/2022 - 08/2012
8	InterferonsIBA 08/2022 - 12/2016
8	AntibodiesIBA 01/2022 - 08/2011
7	Interleukin-2 (IL2)IBA 01/2022 - 04/2015
6	Liposomes (Liposome)IBA 01/2022 - 08/2011
6	Immune Checkpoint InhibitorsIBA 01/2022 - 11/2017
6	LigandsIBA 01/2022 - 12/2009
4	Granzymes (Granzyme)IBA 01/2022 - 01/2017
4	LipidsIBA 01/2022 - 01/2012
4	Neoplasm Antigens (Tumor Antigens)IBA 01/2021 - 03/2013
3	cyclic guanosine monophosphate-adenosine monophosphateIBA 08/2022 - 01/2020
3	Protein Subunit VaccinesIBA 08/2022 - 01/2021
3	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2021 - 12/2009
3	HydrogelsIBA 06/2020 - 09/2008
3	Chimeric Antigen ReceptorsIBA 01/2020 - 01/2018
3	T-Cell Antigen Receptors (T-Cell Receptor)IBA 03/2019 - 08/2012
3	Interleukin-15 (Interleukin 15)IBA 01/2018 - 12/2009
3	Immunologic Factors (Immunomodulators)IBA 01/2017 - 12/2013
3	NanocapsulesIBA 06/2015 - 08/2014
2	Peptides (Polypeptides)IBA 08/2022 - 01/2017
2	Interleukin-12 (IL 12)IBA 01/2022 - 01/2020
2	Glycoproteins (Glycoprotein)IBA 01/2022 - 01/2021
2	Mitoxantrone (Novantrone)FDA LinkGeneric 10/2021 - 12/2017
2	Monoclonal AntibodiesIBA 01/2021 - 01/2019
2	Antiviral Agents (Antivirals)IBA 01/2021 - 01/2014
2	Immunomodulating AgentsIBA 01/2021 - 08/2015
2	Vaccine AdjuvantsIBA 01/2021 - 06/2015
2	RNA (Ribonucleic Acid)IBA 01/2020 - 01/2019
2	GoldIBA 01/2019 - 09/2014
2	InterleukinsIBA 01/2018 - 12/2013
2	AlbuminsIBA 11/2017 - 03/2014
2	Biocompatible Materials (Biomaterials)IBA 01/2017 - 08/2010
2	Chemotactic FactorsIBA 03/2013 - 07/2011
2	NanovaccinesIBA 01/2012 - 01/2012
2	Polysaccharides (Glycans)IBA 03/2011 - 12/2009
1	Complement System Proteins (Complement)IBA 11/2022
1	SolutionsIBA 08/2022
1	Carrier Proteins (Binding Protein)IBA 08/2022
1	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 01/2022
1	Neutralizing AntibodiesIBA 01/2022
1	Pattern Recognition ReceptorsIBA 01/2022
1	MannansIBA 01/2022
1	EpitopesIBA 01/2022
1	aluminum sulfate (alum)IBA 01/2022
1	Etoposide (VP 16)FDA LinkGeneric 10/2021
1	DNA (Deoxyribonucleic Acid)IBA 10/2021
1	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2021
1	Ivermectin (Mectizan)FDA Link 03/2021
1	Adenosine Triphosphate (ATP)IBA 03/2021
1	anthrax toxin (anthrax lethal factor)IBA 02/2021
1	Immunotoxins (Immunotoxin)IBA 02/2021
1	Immunoglobulin G (IgG)IBA 02/2021
1	env Gene ProductsIBA 01/2021
1	resiquimodIBA 06/2020
1	Paclitaxel (Taxol)FDA LinkGeneric 06/2020
1	Interferon Type IIBA 01/2020
1	Antiparasitic Agents (Antiparasitics)IBA 11/2019
1	Chloroquine (Aralen)FDA LinkGeneric 11/2019
1	MitogensIBA 03/2019
1	polyethylene glycol polyethyleneimine nanogelIBA 03/2019
1	Cell-Free Nucleic AcidsIBA 01/2019
1	Cancer VaccinesIBA 01/2019
1	Immunologic Adjuvants (Immunologic Adjuvant)IBA 01/2019
1	AcidsIBA 01/2019
1	LumicanIBA 01/2019

Therapy/Procedure

35	Immunotherapy 08/2022 - 04/2008
27	Therapeutics 01/2022 - 12/2009
4	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2018 - 10/2013
3	Radiotherapy 11/2017 - 09/2014
3	Drug Therapy (Chemotherapy) 01/2017 - 12/2013
2	Injections 06/2020 - 12/2009
1	Neoadjuvant Therapy 01/2022